ALPHA WAVE EXPERIENCE NEUROPHYSIOLOGY RESEARCH.
THE RESEARCH & METHODOLOGY.
SINGLE DAY PLAN OF ACTIVITIES.
OBJECTIVES & END POINTS.
PHYSIOLOGICALLY, WE’RE LOOKING AT THE FOLLOWING BIOMAKERS.
(i) Decrease in EEG frontal Beta activity
(ii) Increase in EEG frontal Theta/ alpha activity
The study population will include 20 subjects residing in Lisbon, Portugal between the ages of 24-46 years old with a mean age of 34 y.o.
the sample was composed of 12 females and 9 males.
1. Provision of signed and dated informed consent form
2. Stated willingness to comply with all study procedures availability for the duration of
3. Males and females; Age 18-65 years.
1. Current use of medications for following mental health conditions; Generalized Anxiety Disorder, Depression, BiPolar Disorder, Schizophrenia, Attention Deficit Disorder, Panic Attack Disorder, Obsessive Compulsive Disorder. In addition, those with past history of substance abuse disorders.
2. Current use of medications for the following physical health conditions; Hypertension, Arrhythmias, Disorders of the Central Nervous System.
3. Implanted pace parker for cardiovascular conditions
5. Hearing deficits such as deafness or hard of hearing.
6. Females that are knowingly pregnant.
HYPOTHESIS TO TEST & DATA ANALYSIS MODEL.
VARIABLES & INSTRUMENTATION.
Neuroguide – EEG (Quantitative Electroencephalogram) Data-Base
BBGuide – Mental State EEG correlation software
ACTIVATION / RELAXATION.
The central nervous system is the part of the nervous system consisting primarily of the brain and spinal cord. The CNS is so named because it integrates the received information and coordinates and influences the activity of all parts of the bodies. The CNS consists of two major structures: the brain and spinal cord. The CNS comprises the Limbic System that supports a variety of functions including emotion, behaviour, long-term memory, and olfaction. Emotional life is largely housed in the limbic system.
The structures and interacting areas of the limbic system are involved in motivation, emotion, learning, and memory. The limbic system operates by influencing the endocrine system and the autonomic nervous system. It is highly interconnected with the nucleus accumbens, which plays a role in sexual arousal and the « high » derived from certain recreational drugs. These responses are heavily modulated by dopaminergic projections from the limbic system. The limbic system is also tightly connected to the prefrontal cortex. Some scientists contend that this connection is related to the pleasure obtained from solving problems. The limbic system interacts heavily with the cerebral cortex. These interactions are closely linked to olfaction, emotions, drives, autonomic regulation, memory, and pathologically to encephalopathy, epilepsy, psychotic symptoms, and cognitive defects. The functional relevance of the limbic system has proven to serve many different functions such as affects/emotions, memory, sensory processing, time perception, attention, consciousness, instincts, autonomic/vegetative control, and actions/motor behavior.
The peripheral nervous system consists of the nerves and ganglia outside the brain and spinal cord. The main function of the PNS is to connect the CNS to the limbs and organs, essentially serving as a relay between the brain and spinal cord and the rest of the body. Unlike the CNS, the PNS is not protected by the vertebral column and skull, or by the blood-brain barrier, which leaves it exposed to toxins and mechanical injuries. The peripheral nervous system is divided into the somatic nervous system and the autonomic nervous system.
The somatic Nervous system (SNS) includes the sensory nervous system and the somatosensory system and consists of sensory nerves and somatic nerves, and many nerves that hold both functions.
The autonomic nervous system (ANS) controls involuntary responses to regulate physiological functions. The brain and spinal cord of the central nervous system are connected with organs that have smooth muscle, such as the heart, bladder, and other cardiac, exocrine, and endocrine-related organs, by ganglionic neurons. The most notable physiological effects from the autonomic activity are pupil constriction and dilation, and salivation of saliva. The autonomic nervous system is always activated but is either in the sympathetic or parasympathetic state. Depending on the situation, one state can overshadow the other, resulting in a release of different kinds of neurotransmitters.
The sympathetic system is activated during a “fight or flight” situation in which mental stress or physical danger is encountered. Neurotransmitters such as norepinephrine and epinephrine are released, which increases heart rate and blood flow in certain areas like muscle, while simultaneously decreasing activities of non-critical functions for survival, like digestion. The systems are independent to each other, which allows activation of certain parts of the body, while others remain rested.
The Parasympathetic system allows the body to function in a “rest and digest” state. Consequently, when the parasympathetic system dominates the body, there are increases in salivation and activities in digestion, while heart rate and other sympathetic responses decrease. Unlike the sympathetic system, humans have some voluntary controls in the parasympathetic system. The most prominent examples of this control are urination and defecation.
We can easily access Central Nervous System emotional states using EEG (electroencephalography) technology and compute indirect metrics of the activation deactivation of the Limbic system.
The theta programme increased the Theta frequency in the frontal area and in the posterior area and reduced the Beta frequency in the frontal and posterior area;
The Beta programme increased the Beta frequency in the frontal area and in the posterior area and reduced the Theta frequency in the frontal and posterior area;
We had marginal significance in the Beta programme increasing frontal Beta;
We had significance in the Beta programme increasing posterior Beta.
THETA PROGRAMME DETAILED RESULTS.
BETA PROGRAMME DETAILED RESULTS.